PolarityTE – Where Self Regenerates Self®

At PolarityTE, we’re aiming to be the first company to truly deliver regenerative medicine into clinical practice, fulfilling the long unmet promise that tissue engineering has failed to achieve. We utilize a patient’s own cells and tissues to regenerate functionally-polarized human tissue. PolarityTE is built on the principle that self must regenerate self. We are revolutionizing regenerative medicine and inducing a paradigm shift through our innovative platform technology, incredible team, expanding network and drive to be different.


Help Us Revolutionize Biomedical Technology

We are looking to partner with people/companies who share our drive and ambition to change the landscape of medicine.

At PolarityTE, our revolutionary platform is being developed to induce cell and tissue polarity, creating uniquely functional tissue to mirror natural development in the human body.

Our Platform is Sparking a Paradigm Shift

At PolarityTE, our revolutionary platform technology is being developed to induce cell and tissue polarity, creating uniquely functional tissue to mirror natural development in the human body.

Our first product targets skin regeneration, with all its layers (dermis, epidermis and hypodermis) and appendages. Skin regeneration will propel us into numerous other arenas, including bone, muscle, fascia, cartilage and nerve.

Our team of seasoned professionals, including a team of reconstructive surgeons, possessing unmatched experience and knowledge of true clinical needs, will drive our platform towards a vast patient impact.

Guided by Our Foundations as Physicians

We are a company created by providers for providers and the patients they serve. Our founders left the practice of medicine to be able to serve more patients on a greater scale. Patients, providers and the advancement of all humanity is at the center of our work, and we are committed to upholding the highest ethical, professional and legal standards as members of the medical and broader global community.

We employ leading healthcare professionals and draw on their clinical experiences to ensure that the needs of providers and patients are at the center of all our work.

Featured Products


Our simple process allows PolarityTE to utilize a small sample of a patient’s own skin to deliver functionally-polarized skin regeneration.



In preclinical models, both cortical and cancellous bone were regenerated using the PolarityTE Platform, which has never been seen before.


Cartilage regeneration may be right around the corner with the PolarityTE platform, which could allow us to battle arthritis with an appropriate weapon – autologous tissue.



It’s time to up the game for soft tissue reconstruction. How about muscle regeneration? At PolarityTE, we aim to make contractile skeletal muscle constructs a reality.


The Holy Grail of tissue engineering – capillary bed formation and a vascular supply. PolarityTE aims to pull it off. Welcome to the Shift®.



Peripheral nerve regeneration has been lacking a key component for decades – cellular support. PolarityTE plans to change that.


Fat grafting has disrupted the field of plastic and reconstructive surgery in recent years. What if you could have an endless supply of fat for future application after a single harvest? On demand autologous fat for your patients? That’s where we’re headed.


Interviews with Executives