Reprise - FloodGate Medical

Advanced Solutions for Healing

About Us

Reprise Biomedical, Inc. is focused on the development and commercialization of biologic medical devices utilizing a proprietary perfusion decellularization process that delivers superior clinical outcomes in a wide variety of surgical procedures. Reprise commenced operations in 2019 as a spin-out from Miromatrix Medical under proprietary technology licensed from the University of Minnesota.

Reprise is led by an experienced medical device management team with a record of success in commercializing biologic medical devices, guided by a Board of Directors with a proven track record of business success.

Look at the Leaders of Reprise

Carrie Powers

President & Chief Executive Officer

Heather Kotila

VP of Human Resources

Tom Kouchoukos

VP of Marketing

Featured Services and Innovations

Miro3D Wound Matrix

Miro3D is designed for use in deep and tunneling wounds

– 2cm thick collagen sheet scaffold designed for deep, tunneling and irregular wounds
– Open and porous acellular graft provides protective environment for wound management
– Cut to desired size for full wall apposition and conformity to wound beds

MiroDry Wound Matrix

MiroDry is designed to conform to any wound bed

– Porcine collagen sheet scaffold
– Compressible and conformable to the irregular wound bed topography
– Innate porosity of the graft provides a protective environment for wound management

MiroTract Wound Matrix

MiroTract is designed for delivery to tunneling wounds or undermining wounds

– Porcine-derived collagen wound matrix compressed on a guidewire
– Expands and relaxes when hydrated for conformity within wound beds
– Porous 3D structure for full wall apposition

MiroDerm Biologic Wound Matrix

Designed for the management of advanced wounds

– Our proprietary perfusion decellularization process results in an open collagen matrix with natural vascular pathways to assist in cellular infiltration and integration
– Offered in different sizes to meet the individual patient’s clinical needs

MiroFlex Biologic Matrix

Designed for soft tissue reinforcement

Unique hepatic-derived surgical matrix that provides an open collagen scaffold with natural vascular pathways; MiroFlex is primed for cellular integration.

– For use in open and laparoscopic hiatal, paraesophageal, parastomal, and ventral hernia repairs
– Ability to be custom shaped and fit through a laparoscopic trocar
– Can be quilted together to reinforce larger hernias

MiroFlex provides a greater degree of cellular integration and remodeling¹, and significantly greater strength of repair²than a dermis-derived competitor* as shown in animal studies.

Company Spotlight Video

News and Stories

Reprise Biomedical’s Miro3D® Wound Matrix Granted Level II HCPCS Code by CMS

Minneapolis, MN, August 28, 2023 – Reprise Biomedical, Inc., a leading innovator in medical biotechnology for wound care, is pleased to announce that the Centers for Medicare and Medicaid Services (CMS) has assigned a Level II Healthcare Common Procedure Coding System (HCPCS) code to its revolutionary Miro3D wound matrix, effective October 1, 2023.

Miro3D is a three-dimensional porcine-derived acellular graft designed to create a protective environment for wounds, specifically for use in cases requiring coverage of and conformance to intricate, tunneling, and irregular wound beds. Available in four sizes, Miro3D features a consistent two-centimeter-thick porous sheet scaffolding structure. When hydrated, Miro3D softens slightly, adapting well to various wound bed shapes and can be fixated to surrounding tissue using preferred methods such as sutures or staples.

Reprise Biomedical Announces U.S. Launch of Miro3D® Three Dimensional Resorbable Wound Matrix

Minneapolis, Minn. (October 6, 2022) – Reprise Biomedical, Inc., an innovative medical device company focused on developing and commercializing biologic solutions using its proprietary perfusion decellularization technology, has commenced U.S. sales of its Miro3D wound matrix through its direct U.S. sales force and independent sales agent network. Reprise received FDA 510(k) clearance for Miro3D on August 18, 2022, and initial clinical evaluations have already been successfully completed.

Miro3D is a three-dimensional (2cm thick) biological matrix designed to be cut and shaped to fill deep or tunneling wound beds. Manufactured from decellularized porcine liver, Miro3D is a highly porous matrix which allows rapid cellular infiltration and integration in situ. Miro3D is the first U.S. commercially available wound matrix that is designed to fill a wound with its three-dimensional scaffold, rather than cover the wound with a traditional two-dimensional wound dressing.

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